Search Results

PKE-AICAR-500 - Acadesine (AICAr): AICAr is a cell-permeable compound whose phosphorylated metabolite activates AMP-activated protein kinase (AMPK). Incubation of rat hepatocytes with the non-phosphorylated AICAR results in accumulation of the monophosphorylated derivative within the ... More
PKE-AICAR-100 - Acadesine (AICAr): AICAr is a cell-permeable compound whose phosphorylated metabolite activates AMP-activated protein kinase (AMPK). Incubation of rat hepatocytes with the non-phosphorylated AICAR results in accumulation of the monophosphorylated derivative within the ... More
9510H - Adiponectin: A DNA sequence encoding the human Adiponectin protein sequence (containing the signal peptide sequence, and the mature Adiponectin sequence) was expressed in modified human 293 cells. Adiponectin is a member of the ‘adipocytokines’ that are cytoki ... More
011-22033 - Anti AGO2 Human, Monoclonal Antibody: Argonaute-2 (AGO2) was isolated as one of the main components of RISC (RNA-induced silencing complex). AGO2 captures siRNAand microRNA which are working as a guide molecule for interaction with target mRNAs in RNAipathway. In this pathway, AGO2 catal ... More
015-22031 - Anti AGO2 Human, Monoclonal Antibody: Argonaute-2 (AGO2) was isolated as one of the main components of RISC (RNA-induced silencing complex). AGO2 captures siRNAand microRNA which are working as a guide molecule for interaction with target mRNAs in RNAipathway. In this pathway, AGO2 catal ... More
018-22021 - Anti AGO2 Mouse, Monoclonal Antibody: Argonaute-2 (AGO2) was isolated as one of the main components of RISC (RNA-induced silencing complex). AGO2 captures siRNAand microRNA which are working as a guide molecule for interaction with target mRNAs in RNAipathway. In this pathway, AGO2 catal ... More
014-22023 - Anti AGO2 Mouse, Monoclonal Antibody: Argonaute-2 (AGO2) was isolated as one of the main components of RISC (RNA-induced silencing complex). AGO2 captures siRNAand microRNA which are working as a guide molecule for interaction with target mRNAs in RNAipathway. In this pathway, AGO2 catal ... More
017-19781 - Anti Rat VGLUT-2, Rabbit: L-Glutamate is an excitatory chemical transmitter that plays an essential role in neuronal plasticity, behavior, learning and central nervous system. VGLUTs play an essential role in glutamate signal output through vesicular storage of L-glutamate. ... More
010-19771 - Anti VGLUT-1 Rat, polyclonal, Rabbit: L-Glutamate is an excitatory chemical transmitter that plays an essential role in neuronal plasticity, behavior, learning and central nervous system. VGLUTs play an essential role in glutamate signal output through vesicular storage of L-glutamate. ... More
305-31891 - Anti-AdipoR1 Human Polyclonal Antibody: PPAR agonists are reported to increase expression of activated adiponectin. PPAR-gamma agonists also increase expression of adiponectin receptors (Ref.2). Such findings have focused attention on the role of AdipoR1 in PPAR agonist development. Thi ... More
30600302 - Cathepsin G: Polymorphonuclear leukocytes (PMNs) contain abundant amounts of antibacterial proteins and proteolytic enzymes within peroxidase-positive azuphil granules. Some of these proteins show a spectrum of antibiotic activities and are collectively termed se ... More
30600303 - Cathepsin G: Polymorphonuclear leukocytes (PMNs) contain abundant amounts of antibacterial proteins and proteolytic enzymes within peroxidase-positive azuphil granules. Some of these proteins show a spectrum of antibiotic activities and are collectively termed se ... More
3081C - Cripto-1: Cripto plays critical roles during embryogenesis and has been implicated in promoting the growth and spread of tumors. Cripto is required for signaling by certain transforming growth factor-2 superfamily members, such as Nodal, but also antagonizes o ... More
3081D - Cripto-1: Cripto plays critical roles during embryogenesis and has been implicated in promoting the growth and spread of tumors. Cripto is required for signaling by certain transforming growth factor-2 superfamily members, such as Nodal, but also antagonizes o ... More
3081H - Cripto-1: Cripto plays critical roles during embryogenesis and has been implicated in promoting the growth and spread of tumors. Cripto is required for signaling by certain transforming growth factor-2 superfamily members, such as Nodal, but also antagonizes o ... More
9002H - EPO R - Fc Chimera: EPO (aka. erythropoetin or hematopoietin ) is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow. It is produced by the peritubular capill ... More
9002I - EPO R - Fc Chimera: EPO (aka. erythropoetin or hematopoietin ) is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow. It is produced by the peritubular capill ... More
291-59201 - GLP-1 ELISA Kit, Rat: Glucagon-like peptide-1 (GLP-1) is an incretin hormone, which is synthesized in intestinal endocrine cells. This peptide is known to increase insulin secretion by glucose stimulation and suppress glucagon secretion. The kit is applicable to measure r ... More
292-60601 - GLP-2 ELISA Kit, Rat: Proglucagon is processed to GLP1 and GLP2 in intestinal L cells. It is reported that GLP-2 is a neurotransmitter involved in the regulation of food intake. The kit is able to measure GLP-2 in rat serum and plasma. ... More
P30227 - GLP2R-tGFP/CHO-K1 Fluorescent Glucagon-like peptide-2 Internalization Assay Cell Line: GLP2R-tGFP/CHO-K1 Fluorescent Glucagon-like peptide-2 Internalization Assay Cell Line ... More
297-57101 - Glucagon ELISA KIT, Rat: Glucagon is known as a hormone secreted from the pancreas and intestines. This kit aims at measurement of rat Glucagon peptide secreted from pancreatic a-cells by competitive format. Pancreatic Glucagon plays a important role in regulating sugar leve ... More
PKI-HA1004-010 - HA-1004: Inhibitor of cAMP- and cGMP-dependent kinases (PKA/PKG, IC50 ~1-2uM). Also inhibits CaMKII, PKC and MLCK at higher concentrations. Intracellular Ca2+ antagonist with no effect on cardiac function. Causes selective pulmonary vasodilation during pulmon ... More
PKI-HA1004-025 - HA-1004: Inhibitor of cAMP- and cGMP-dependent kinases (PKA/PKG, IC50 ~1-2uM). Also inhibits CaMKII, PKC and MLCK at higher concentrations. Intracellular Ca2+ antagonist with no effect on cardiac function. Causes selective pulmonary vasodilation during pulmon ... More
PKI-HA1077-025 - HA-1077, fasudil: Inhibitor of ROCKII, Rho kinase, PRK2 and MSK1, also inhibits PKA, PKG, S6K1 and MAPKAP-K1b, myosin light chain kinase (MLCK) and Ca2+/calmodulin dependent protein kinase II (CaMKII). Cell permeable Ca2+ antagonist with antivasospastic properties. ... More
PKI-HA1077-010 - HA-1077, fasudil: Inhibitor of ROCKII, Rho kinase, PRK2 and MSK1, also inhibits PKA, PKG, S6K1 and MAPKAP-K1b, myosin light chain kinase (MLCK) and Ca2+/calmodulin dependent protein kinase II (CaMKII). Cell permeable Ca2+ antagonist with antivasospastic properties. ... More
P30101 - HEK293-ADRB3 Adrenergic-beta 3 receptor stable expressing HEK293 Cell Line: The beta-3 adrenergic receptor (beta-3 adrenoreceptor), also known as ADRB3, is an beta-adrenergic receptor, and also denotes the human gene encoding it. Actions of the beta-3 receptor include enhancement of lipolysis in adipose tissue & thermogenesi ... More
P30113 - HEK293-GLPR2 Glucagon-like peptide-2 stable expressing HEK293 Cell Line: HEK293-GLPR2 Glucagon-like peptide-2 stable expressing HEK293 Cell Line ... More
30600103 - Human HtrA1 (His-tagged), Recombinant: Secreted human HtrA1 serine protease is supposed to form oligomers of identical protein chains as revealed by X-ray analysis for the bacterial HtrA protein DegP. Polypeptide chains of human HtrA1 consist of several domains: An N-terminal insulin-like ... More
30600102 - Human HtrA1 (His-tagged), Recombinant: Secreted human HtrA1 serine protease is supposed to form oligomers of identical protein chains as revealed by X-ray analysis for the bacterial HtrA protein DegP. Polypeptide chains of human HtrA1 consist of several domains: An N-terminal insulin-like ... More
9007H - IFNAR2 - Fc Chimera: A DNA sequence encoding the signal peptide and extracellular domain of human IFNAR2 (aa 1-243) was fused to the Fc region of human IgG1 (aa 90-330). The chimeric protein was expressed in modified human 293 cells. Type I interferons (IFN alpha, beta, ... More
4012D - IL-12: A DNA sequence encoding the human IL-12 protein sequence (containing the signal peptide and the mature IL-12 alpha chain sequence, and the signal peptide and the mature IL-12 beta chain sequence) was expressed in modified human 293 cells. Human in ... More
4012C - IL-12: A DNA sequence encoding the human IL-12 protein sequence (containing the signal peptide and the mature IL-12 alpha chain sequence, and the signal peptide and the mature IL-12 beta chain sequence) was expressed in modified human 293 cells. Human in ... More
4012H - IL-12: A DNA sequence encoding the human IL-12 protein sequence (containing the signal peptide and the mature IL-12 alpha chain sequence, and the signal peptide and the mature IL-12 beta chain sequence) was expressed in modified human 293 cells. Human in ... More
4100C - IL-1ra: A DNA sequence encoding the human Interleukin-1 receptor antagonist (IL-1ra) protein sequence (including the signal peptide sequence, and the mature human Interleukin-1 receptor antagonist sequence) was expressed in modified human 293 cells. IL-1 ... More
4100D - IL-1ra: A DNA sequence encoding the human Interleukin-1 receptor antagonist (IL-1ra) protein sequence (including the signal peptide sequence, and the mature human Interleukin-1 receptor antagonist sequence) was expressed in modified human 293 cells. IL-1 ... More
4003D - IL-3: A DNA sequence encoding the human Interleukin 3 protein sequence (containing the signal peptide sequence, and the mature human Interleukin 3 sequence) was expressed in modified human 293 cells. Interleukin-3 (IL-3) is a pleiotropic cytokine that r ... More
4003G - IL-3: A DNA sequence encoding the human Interleukin 3 protein sequence (containing the signal peptide sequence, and the mature human Interleukin 3 sequence) was expressed in modified human 293 cells. Interleukin-3 (IL-3) is a pleiotropic cytokine that r ... More
4003C - IL-3: A DNA sequence encoding the human Interleukin 3 protein sequence (containing the signal peptide sequence, and the mature human Interleukin 3 sequence) was expressed in modified human 293 cells. Interleukin-3 (IL-3) is a pleiotropic cytokine that r ... More
630-07103 - Insulin Standard Solution, Humster (10ng/ml): Insulin is a hormone that is central to regulating carbohydrate and fat metabolism in the body. Insulin causes cells in the liver, muscle, and fat tissue to take up glucose from the blood, storing it as glycogen in the liver and muscle. Insulin stop ... More
637-07113 - Insulin Standard Solution, Rabbit (10ng/ml): Insulin is a hormone that is central to regulating carbohydrate and fat metabolism in the body. Insulin causes cells in the liver, muscle, and fat tissue to take up glucose from the blood, storing it as glycogen in the liver and muscle. Insulin stop ... More
9501C - Leptin: A DNA sequence encoding the human Leptin protein sequence (containing the signal peptide sequence, and the mature Leptin sequence) was expressed in modified human 293 cells. Leptin, also known as obesity factor and obese protein, is a member of th ... More
1003H - MC-148-Fc Chimera: A DNA sequence encoding MC-148 (aa 1-106) was fused to the Fc region of human IgG1 (aa 93-330). The chimeric protein was expressed in modified human 293 cells. MC-148 is a viral chemokine synthesised by the human poxvirus, Molluscum contagiosum vi ... More
1003I - MC-148-Fc Chimera: A DNA sequence encoding MC-148 (aa 1-106) was fused to the Fc region of human IgG1 (aa 93-330). The chimeric protein was expressed in modified human 293 cells. MC-148 is a viral chemokine synthesised by the human poxvirus, Molluscum contagiosum vi ... More
6005C - NT-3: A DNA sequence encoding the human NT-3 protein sequence (containing the signal peptide and the mature NT-3 sequence) was expressed in modified human 293 cells. Neurotrophin-3 (NT-3), also known as nerve growth factor-2 (NGF2) or hippocampus-derive ... More
6005B - NT-3: A DNA sequence encoding the human NT-3 protein sequence (containing the signal peptide and the mature NT-3 sequence) was expressed in modified human 293 cells. Neurotrophin-3 (NT-3), also known as nerve growth factor-2 (NGF2) or hippocampus-derive ... More
30600202 - Neutrophil Elastase: Leukocyte elastase is one of several hydrolytic enzymes contained in the azurophil granules of human neutrophils exhibiting a relative molecular weight of 29.5 kDa. The enzyme differs from pancreatic elastase in specificity on synthetic substrates an ... More
30600203 - Neutrophil Elastase: Leukocyte elastase is one of several hydrolytic enzymes contained in the azurophil granules of human neutrophils exhibiting a relative molecular weight of 29.5 kDa. The enzyme differs from pancreatic elastase in specificity on synthetic substrates an ... More
SY-3MA - PI3-kinases/Autophagy inhibitor - 3-MA (3-Methyladenine): 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI3K) via ATP competition. Please inquire about pricing for 100mg size ... More
PKI-PHLRTN-250 - Phloretin: Phloretin (from apple root extract) is a cell-permeable PKC inhibitor and a PGF2a receptor antagonist, purity: > 98% (HPLC) ... More
PKI-PHLRTN-1000 - Phloretin: Phloretin is a cell-permeable protein kinase C (PKC) inhibitor (IC50 = 20-50 �M) and a PGF2a receptorantagonist. In astrocytes, these receptors are linked to phospholipase C, thus affecting phosphoinositide hydrolysis and intracellular Ca2+ levels. I ... More
30600112 - Recombinant Human HtrA1, truncated, His-tagged: Secreted human HtrA1 serine protease is supposed to form oligomers of identical protein chains as revealed by X-ray analysis for the bacterial HtrA protein DegP [1]. Polypeptide chains of human HtrA1 consist of several domains: An N-terminal insulin- ... More
30600113 - Recombinant Human HtrA1, truncated, His-tagged: Secreted human HtrA1 serine protease is supposed to form oligomers of identical protein chains as revealed by X-ray analysis for the bacterial HtrA protein DegP [1]. Polypeptide chains of human HtrA1 consist of several domains: An N-terminal insulin- ... More
9014I - TrkC - Fc Chimera: A DNA sequence encoding the signal peptide and extracellular domain of human TrkC (aa 1-428) was fused to the Fc region of human IgG1 (aa 93-330). The chimeric protein was expressed in modified human 293 cells. TrkC, also known as neurotrophic tyr ... More
PKI-W7-025 - W-7: W7 is a calmodulin antagonist, inhibits Ca2+/calmodulin-regulated enzyme activities of MLCK and PDE-1, purity: > 97% (HPLC) ... More
PKI-W7-050 - W-7: W7 is a calmodulin antagonist that binds to calmodulin and inhibits Ca2+ / calmodulin-regulated enzyme activities of myosin light chain kinase (MLCK, IC50 = 51 uM) and Ca2+ / calmodulin-regulated phosphodiesterase (PDE I, IC50 = 28 uM). It is also a ... More
PK-PKACR2A025 - cAMP-dependent protein kinase, holo enzyme complex, type II alpha (PKA C2RIIA2): cAMP-dependent protein kinase (PKA) is an ubiquitous serine/theonine protein kinase present in a variety of tissues (e.g. brain, skeletal muscle, heart). The intracellular cAMP level regulates cellular responses by altering the interaction between th ... More
292-66701 - microRNA Isolation kit, Human Ago2: microRNA Isolation kit, Human Ago2 ... More