Go Back Anti-NADase (hemolytic streptococcus) antibody rabbit serum

Product Detail

Cat # 64-006
Size 250 ul
Price $545.45
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E64-006anti-NADase.pdf

NAD (nicotinamide adenine dinucleotide) hydrolyzing enzyme is one of the extracellular enzymes and toxins produced by hemolytic streptococci. Although the function as a toxin is largely unknown, it has been suggested to be related to pathogenicity of acute infection (1). NADase is produced not only by Group A hemolytic streptococci but also by Group C and Group G strains. The amino acid sequences are highly conserved among them and the antibodies cross-react each other. Upon infection of hemolytic streptococci, the antibody titer to the NADase is increased similarly to anti-SLO (Strreptolysin O) antibody. The product was prepared by immunizing rabbit with purified recombinant NADase of Group C hemolytic streptococci expressed in E. coli (2).

Application 1) Western blotting (x2,000~10,000 dilution*) 2) Immunoprecipitation 3) Neutralization of NADase activity

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