Endothelin Receptor Type A stable expressing U2OS cell line


Categories: Cells

Innoprot HiTSeeker EDNRA Cell Line has been designed to assay compounds or analyze their capability to modulate Endothelin Receptor type A. When Endothelin I binds to the EDNRA a G protein is activated, which in turn, triggers a cellular response mediated by second messengers (Ca). This cell line has been validated measuring Calcium increase in the cytosol. The high reproducibility of this assay allows monitoring Endothelin Receptor type A? activation process in High Throughput Screening.