Go Back Anti PPARgamma Human, Polyclonal Antibody
Product Detail
| Cat # | 308-31881 |
| Size | 100 ug |
| Price |
$512.00 |
| Downloads | |
The PPAR-gamma subtype was originally identified as a factor binding to a fatty acid specific enhancer of the aP2 gene. PPAR-gamma actions are mediated by three isoforms resulting from alternative promoter selection and alternative splicing. PPAR-gamma1 is widely expressed while PPAR-gamma2 expression is restricted to adipose tissue and PPAR-gamma3 expression is restricted to adipose tissue, macrophage, and colon.
PPAR-gamma participates in adipose cell differentiation and energy storage (Ref.1). Recently, these roles of PPAR-gamma have focused attention on PPAR-gamma as a target of the anti-diabetic thiazolidinedione class of drugs. This antibody was prepared from the serum of a rabbit immunized with a partial peptide representing the C-terminal domain of Human PPARgamma, and purified by peptide affinity chromatography. Working dilution for Western blotting is 1.0?g/ml.