Go Back Anti CML Monoclonal Antibody (NF1G)

Product Detail

Cat # 303-09961
Size 50 ug
Price $722.00
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datasheet.pdf

N-(carboxymethyl)lysine (CML) is a major antigenic AGEs structure in vivo and is known to be generated from Oxidative cleavage of Amadori product. In addition to amadori product, CML formation also takes place through glyoxal, which is generated from the autoxidation of glucose and unsaturated fatty acids. NF-1G is monoclonal antibody specific for CML and useful for immunohistochemical staining to demonstrate the localization of CML in some pathological tissues.

The splenic lymphocytes from BALB/c mouse, immunized with CML-HSA were fused to myeloma P3U1 cells. The cell line (NF-1G) with positive reaction was grown in ascitic fluid of BALB/c mouse, from which the antibody was purified by Protein G affinity chromatography.

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