Go Back Anti CML Monoclonal Antibody (Clone:CMS-10)
Product Detail
| Cat # | 302-08831 |
| Size | 50 ug |
| Price |
$722.00 |
| Downloads | |
N-(carboxymethyl)lysine (CML) was a major AGEs structure identified by Banes et al. in 1989. Oxidative cleavage of Amadori products is considered as a major route to CML formation in vivo. Banes also revealed that CML was directly formed from the reaction between lipidoxidative products and Lysine residue. Thus, CML could become a marker of oxidative stress and long term damage to protein in aging, atherosclerosis, and diabetes.����The splenic lymphocytes from BALB/c mouse, immunized with CML-KLH were fused to myeloma P3U1 cells. The cell line (CMS-10) with positive reaction was grown in ascitic fluid of BALB/c mouse, from which the antibody was purified by Protein G affinity chromatography.