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Product Detail

Cat # PKI-PP2-005
Size 5 mg
Price $504.00
Qty

Potent and selective inhibitor of the src family of tyrosine kinases. Selectively inhibits Lck (IC50 approx. 4nM), Fyn (IC50 approx. 5nM) and Hck (IC50 approx. 5nM) compared to other tyrosine kinases such as EGF-R (IC50 approx. 480nM), JAK2 (IC50 approx. 50uM) or ZAP-70 (IC50 approx.100uM). Potent inhibitor of anti-CD3-stimulated tyrosine phosphorylation of human T-cells and subsequent IL-2 gene activation.

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