Go Back Yes
Product Detail
| Cat # | PK-YES-A010 |
| Size | 10 ug |
| Price |
$424.00 |
Yes is a cytosolic ubiquitously expressed tyrosine kinase, sharing a high sequence similarity to Src. As all Src family members Yes is formed of an N-terminal membrane localization domain, a poorly conserved unique domain, an SH3 domain, an SH2 domain, a tyrosine kinase domain and a short carboxyterminal regulatory sequence. Yes is activated downstream of a multitude of cell surface receptors and during the cell cycle transition. Activated kinase is involved in different signaling processes such as proliferation, survival and regulation of the cytoskeleton e.g. the formation of the tight junction.