Rat Microglia (RM) provided by Innoprot are isolated from culture rat brain tissue. RM are cryopreserved after purification without further expansion and delivered frozen. Microglia, one of the glial cell types in the CNS, are an important integral component of neuro-glial cell network. Microglia act as brain macrophages when programmed cell death occurs during brain development or when the CNS is injured. Microglia are involved in a variety of physiological and pathological processes in the brain by interacting with neurons and other glial cells and through production of biologically active substances such as growth factors, cytokines, and other factors.