Go Back anti-Sup35 (anti-PSI+, S.cerevisiae) antibody, rabbit polyclonal IgG

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Cat # 62-300
Size 100 ul
Price $363.64
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E62-300 anti-Sup35 PSI+.pdf

Sup35 protein of S. cerevisiae is the translation termination factor eRF3. The altered conformation of this protein generates the [PSI+] prion phenotype (1). In this state, a dominant cytoplasmically inherited protein aggregates are formed which sequester the normal function of Sup35 thereby nonsense suppressor phenotype is created (2). The molecular chaperon Hsp104 is necessary for the formation and maintenance of the aggregates (3, 4).

Applications Western blotting (1,000~2,000* fold dilution). Not tested for other applications.

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