Go Back Anti-PTEN

Product Detail

Cat # 3029
Size 100 ug
Price $250.00
Qty
Downloads

PTEN-datasheet.pdf

The PTEN gene (aka MMAC1 and TEP1) is a candidate tumor suppressor gene. Mutations of PTEN are implicated in sporadic brain cancer, breast, kidney and 60-80% of prostate cancers. PTEN functions primarily as a lipid phosphatase to regulate signal transduction pathways; a key target is phosphatidylinositol 3,4,5 trisphosphate, a signalling inositol phospholipid generated by PI3K activity.

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