Go Back Aggrecanase Activity Assay, human
Product Detail
| Cat # | 30510111 |
| Size | 96 tests |
| Price |
$720.00 |
| Downloads | |
Human Aggrecanase Activity Assay for quantitative determination of aggrecanase activity For screening and evaluation of aggrecanase inhibitors.
The InviLISA Aggrecanase Activity Assay measures activity of aggrecanases. It is used to screen and characterize aggrecanase inhibitors. It consists of two modules: Aggrecanase module and the ELISA module. In this Assay a recombinant fragment of human aggrecan interglobular domain (aggrecan-IGD) is first digested with aggrecanase (ADAMTS4). The proteolytic cleavage of the substrate releases an aggrecan peptide with the N-terminal sequence ARGSVIL (ARGSVIL-peptide). The ARGSVIL-peptide-s is then quantified with two monoclonal anti-peptide antibodies.
For research use only. Not for diagnostic use.